Flumetone

Other names kill it, WL108366

(I) Properties and effects Fluotrione pure product is off-white crystalline powder, almost insoluble in water, insoluble easily forms water-soluble strong alkali salts, and slightly soluble in water. This product is anticoagulant rodenticide, does not produce no diet on rodents. Flumetone is a patented rodenticide from British Shell Chemical Company in 1984. Its chemical structure and biological activity are similar to those of Dalong, the second-generation anticoagulant. It has a good control effect on various rodents, including the first-generation anticoagulant-resistant mice, and has good palatability. According to China's pesticide toxicity grading standard, Flumetone is a highly toxic rat killer. The acute oral LD50 of the original drug is 0.25 mg/kg in rats. The acute virulence is large. The rats can achieve the purpose of prevention and control once they ingest food. One lethal dose is absorbed within 3 to 10 days after death, and one dose can be used. It is safer for non-target animals, including lower acute virulence to birds. Dogs are very sensitive to Flumettanone. Toxicity to pigs is 175 times less than that of rats. This selective toxicity is superior to other rodenticides of the same type.

Flumettanone is suitable for indoor and outdoor farms to prevent and control various rodents. And there is a special antidote to vitamin K1.

(b) Preparation

1.0.005% poison bait, scattered grain (wheat and rice) bait and wax block, wax bait.

2.0.1% of the powder, this dosage form plus grain bait dubbed 0.005% bait use.

Preparation method:

(1) Sticking method Mix 0.5 parts of edible oil or rice soup with 19 portions of bait (you can choose fresh cereals that the mouse prefers to eat according to the specific conditions of each place), mix well, and coat each piece of bait with a layer of oil film or rice soup, then add A 0.1% powder is evenly mixed and made into a 0.005% kill bait.

(2) Preparation of bait by water immersion method First, the bait grain is soaked in water until swollen, and after drying, take 19 parts of bait and add 1 part of 0.1% powder to mix well.

(III) How to use

1. The control of Rattus norvegicus in farmland in the south of China has to be carried out twice a year for total rodent extermination and once for local rodent eradication. The early rodent extermination period was appropriate in February; late rice was carried out in August. Based on the behavior of the Rattus norvegicus and its ecological habits, using the characteristics of the relatively concentrated nature of the nesting area, the focus of the poisonous bait on the main inhabitation of mangroves, banana land, irrigation and drainage channels and ponds, etc. is higher than that of paddy fields, fields and fields, and long-term loss. Five sides of the grass. Use 0.005% to kill it indica rice baits, use 150-160 grams of bait per acre, ribbon cast, Putian 5-6 per acre feeding points, each point 20 grams of poison bait, one poison can be. Honda kills 25 mu of poison baits per person per day and uses it to kill poisonous baits and save food. The effect of rodent control is generally over 90%.

2. Control Rattus norvegicus use 0.005% to kill it.

(1) Indoor poison baits, Rattus norvegicus prefer to inhabit in stable locations with stable temperature and humidity. Mouseholes are excavated around house foundations, garbage dumps, basements, wall bases, sewers, kitchens, and warehouses. There are migration habits, winter migration to the indoor winter, the best indoor rodents in early spring and autumn and winter seasons, pay attention to these types of places when bait poisoning, can be appropriate to vote more. The amount of poison bait, each room (15 square meters) cast 1-2 points, 3-5 grams per point, saturated feeding, or a feeding, appropriate increase in the amount of feeding, the killing rate can reach More than 90.

(2) Poisoned bait in the field In summer and autumn, the food in the field is abundant. The Rattus norvegicus migrates to the outdoor road near the village, on both sides of the road, Tian Tan, the four sides, the grave mound, the irrigation channel, the edge of the pond, and the alluvial land along the river bank. When paying poison bait, pay attention to such places. In the field, the bait can be baited by 510 (square meters) and each shot is 3-5 grams. In the spring and seasonal seasons, it is effective to choose poison baits when field food is lacking.

3. Prevention and control of small rats According to foreign reports, in the farm barn, livestock feed warehouse and application granary with 0.005% to kill it oatmeal baits, the control effect of 87.1% -100%.

4. Prevention and control of Mongolian gerbils in the pastoral areas and agricultural and pastoral areas in control of Mongolian gerbils, the rat hole is obviously easy to find, you can throw 0.005% to kill it and kill poison baits, each hole cast 1 gram bait; or press 520 (m2) Isometric shots, 50-75 grams of poison bait per acre can be dispensed. If the mouse density is too high and there are more than 2000 mouse holes per hectare, the amount of poisoned baits will increase appropriately. Equivalent injection of poison bait is more effective than depositing baits by hole, and the cost is low.

5. Prevention and control of Brandt's voles in the grasslands in spring, the density of rats is higher, the number of holes per hectare is more than 385, there are 23 rats when the control index is reached, use 0.005% to kill it and bait baits, 1000 grams of baits per hectare (ie use per acre 66.7 grams of poisonous baits. The poison baits scattered on the ground must not be piled up, making it difficult for mice to eat them once and eat them or eat them until they are fully discharged within a day. The chronic virulence characteristics of the agent enhance the efficacy and efficiency of work, and also facilitate the use of mechanical and aircraft feeding.

(4) Precautions

1. Avoid contact with skin, eyes, nose or mouth when using this medicine;

2. After the drug is used, clean up the bait package and bury or burn the dead body of the mouse;

3. Prevent children, livestock, and birds from approaching poison baits;

4. Flumetone is sensitive to dogs and geese and should be used when used.

5. Prepare antidotal agent vitamin K1 in advance when using drugs;

6. There are many species of rodent pests in China's agriculture, animal husbandry, and forestry regions, and it is best to apply them before testing with Flumettanone.

7. Flumetone poisoning First aid: Fluorobetaine is the second generation of anticoagulant rodenticide. After animal feed, it is absorbed mainly in the gastrointestinal tract. After oral administration, it begins to absorb in a few minutes, and it lasts for 2-3 days. Its mode of action is 7. Is the inhibition of vitamin K synthesis, low-dose poisoning, generally without any symptoms. The main manifestations of these symptoms are urine, nasal blood, or bloody discharges from the eye, subcutaneous hematoma, bleeding from the gums, and tar excretion in the stool. Severe symptoms such as abdominal pain and back pain are unconscious. Poisoned animals died of major bleeding. It was found that eating indiscriminately and quickly sent to the hospital for 4 to 5 days, because the mechanism of action of this type of drug is not yet fully understood, and in addition to anticoagulant effects, it must have other toxicological effects.

Clinical diagnosis, using the Quaker test to determine plasma prothrombin time is a sensitive and reliable diagnostic method. Patients who ingest poisoning can detect a prolonged prothrombin time within 24-48 hours. The normal prothrombin time is 121 seconds. If prothrombin time is prolonged, vitamin K1 should be injected intramuscularly, 5-10 mg for adults and 1-5 mg for children. The prothrombin time was measured after 24 hours. If no shortening was observed, intramuscular injection of vitamin K1 was continued with the same dose. For patients with severe bleeding, especially if the intramuscular injection causes hematoma, intravenous vitamin K1 is administered at a dose of 25 mg for adults and 0.6 mg/kg for children, once a day until symptoms disappear. Vitamin K1 can also be intravenously diluted with grapevine saline. Usually 3-6 hours to control bleeding symptoms. If there is a small amount of asymptomatic and asymptomatic, generally no treatment or protective treatment is performed, oral vitamin K1 adult 15-25 mg, children 5-10 mg.

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