Treatment of indirect optic nerve injury and analysis of visual prognosis

Release date: 2007-10-17

Treatment of indirect optic nerve injury and visual prognosis analysis Vision is no light perception, coma, optic canal fracture, craniocerebral injury, high age, and the first improvement in visual acuity are the risk factors for visual prognosis in patients with indirect optic nerve injury, and residual visual acuity after injury The situation is directly related to the patient's visual prognosis; optic canal decompression is beneficial to the prognosis of residual visual eye after injury, and the effect of combination therapy is better than drug therapy alone. Generally, severe trauma can cause optic nerve injury or neural tube fracture, which leads to damage or compression of optic nerve fibers. Optic nerve contusion often occurs in the optic canal and intracranial segment. Optic nerve trauma often occurs in accidents such as car accidents and fighting. In the third issue of the March issue of the Chinese Journal of Ophthalmology, a study was conducted to investigate the clinical data of 186 patients with indirect optic nerve injury. The factors affecting visual prognosis were analyzed and the clinical effects of drug therapy and combination therapy were compared. To investigate the influencing factors of visual prognosis in patients with indirect optic nerve injury, and to evaluate the simple drug treatment (glucocorticoid-based, energy mixture, neurotrophic, dehydration, improvement of vascular microcirculation and other conventional drugs) and combined therapy (optic nerve decompression plus above) The clinical effect of the drug).
Researchers from the Department of Ophthalmology of the General Hospital of the People's Liberation Army Zhang Ying and other researchers showed that of the 186 patients, 67 (36.02%) had improved vision and 51 recovered visual center vision. The final visual acuity was better than the post-injury visual acuity (P<0.01). ). The visual acuity improvement rate of 136 cases with no light perception was only 25.74%, which was 42.26% lower than that of residual visual acuity (P<0.01). There was a statistically significant difference in the efficacy between combination therapy and drug alone (P<0.01). Logistic regression analysis showed that the surgical treatment was effective for the improvement of visual acuity in the residual visual acuity (P<0.01). Post-injury coma was a risk factor for the prognosis of optic nerve injury (P<0.05). Residual vision eye after injury, optic canal fracture, craniocerebral injury, high age, and the first improvement of visual acuity are the risk factors affecting the visual prognosis of patients. The timely surgical treatment after optic nerve injury is a favorable measure to protect vision. The residual visual acuity values ​​were positively correlated with the final visual acuity and visual acuity recovery values, respectively. Therefore, visual acuity is no light perception, coma, optic canal fracture, craniocerebral injury, high age, and the first improvement of visual acuity are the risk factors for visual prognosis in patients with indirect optic nerve injury. The residual visual acuity after injury is directly related to the patient's vision. Prognosis; optic canal decompression is beneficial to the prognosis of residual visual acuity after injury. The effect of combination therapy is better than that of drug alone. ——Midi Medical Network

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