Japanese studies show that genetically variable obese people can lose weight without genetic methods

According to a Xinhua News Agency, Tokyo, November 10 (Reporter Qian Wei) A Japanese survey showed that people who are obese due to genetic variation can also be significantly slimmed down by ordinary weight-loss methods. There is no need to use some gene-regulated methods promoted by institutions.
According to the Japanese "Daily News" report, some Japanese organizations have announced that the gene weight loss law claims that people who are obese due to genetic variation must undergo the gene weight loss method, that is, to achieve slimming effect by controlling gene expression or genetic modification technology, but the University of Tohoku The findings of researchers such as Li Shanjin, an associate professor of public health, contradict this view.
Li Shanjin et al. performed a physical examination on 37 people aged 40 to 69 who participated in weight loss training classes in Fukushima Prefecture, mainly to check whether their β3-adrenergic receptor gene was mutated and its effect on weight loss. Relationship between. The β3-adrenergic receptor gene is a representative gene associated with obesity. Some researchers believe that the mutant has a lower basal metabolic level than a person with no mutation in this gene, and thus is prone to obesity.
The survey showed that 12 of the 37 people had mutations in the β3-adrenergic receptor gene. The BMI body mass index of these 12 individuals, ie the average body weight (kg) divided by the height (m) squared, was 25.6, and the average BMI body mass index of the remaining unmutated genes was 24.8.
Professional hygienists and nutrition managers performed a six-month diet and exercise instruction on these 37 individuals based on the general weight loss method. The results showed that 12 individuals with a β3-adrenergic receptor gene variant had an average weight loss of 2.52 kg and a BMI of 1.08. The average weight of the mutant without the gene was reduced by 1.89 kg and the BMI index decreased by 0.8. Japanese researchers believe that the two sets of data show that obese people due to genetic problems can also be significantly slimmed down by ordinary weight-loss methods.

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